Communities
The OpenTox community is developing an Open Source-based predictive toxicology framework that provides a unified access to toxicological data and models. OpenTox provides tools for the integration of data, for the generation and validation of in silico models for toxic effects, libraries for the development and integration of modelling algorithms, and scientifically sound validation routines. OpenTox supports the development of applications for non-computational specialists in addition to interfaces for risk assessors, toxicological experts and model and algorithm developers. OpenTox is tailored especially to meet the requirements of the REACH legislation and to contribute to the reduction of animal experiments for toxicity testing. The impact of OpenTox should, however, go beyond REACH and industrial chemicals, because reliable toxicity estimates are also needed for other products (e.g. pharmaceuticals, cosmetics, food-additives) and endpoints. The OpenTox framework works independently of any specific algorithm, dataset or endpoint thus providing an extendable capability for the building of many different resources and applications in predictive toxicology.
Collaborative Research in Drug Discovery: The eCheminfo Collaboration Pool of individuals and organisations has an interest in collaborating together in areas of drug discovery. For example, a selection of Pool members can participate in a collaborative drug discovery or predictive ADME/Tox project, develop a funding proposal or response to a call opportunity together, or develop an innovation or best practice. Collaborations take a virtual organisation approach, i.e., partners can bring contributing modelling or experimental capabilities to a partnership for the duration of a project or other endeavour.
InnovationWell is a member-based network and Community of Practice (CoP) of experts, researchers and executives with a common interest in innovation and knowledge management in the pharmaceutical, life science and healthcare sectors and in delivering knowledge-based solutions and services in areas of unmet need. The InnovationWell Community’s program has the goal of achieving improved patient safety, enhancing outcomes in healthcare product development & delivery, reducing costs and improving productivity and quality through cross-disciplinary and cross-organisational use of innovative technologies, knowledge-based strategies and supporting integrated and semantic-based informatics systems.